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Pancreatic amylin dynamically reconfigures distributed brain networks governing appetite regulation in mice | Synapse
March 3, 2026
Open Access
Pancreatic amylin dynamically reconfigures distributed brain networks governing appetite regulation in mice
IG
Irmak Gezginer
University of Zurich
GM
Giulia Mazzini
University of Helsinki
CF
Christelle Le Foll
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Puntos clave
Pancreatic amylin alters appetite regulation by dynamically changing brain network activity, affecting food intake.
Key metric findings indicate that specific brain regions responsive to amylin influence appetite behavior in 30 male mice.
Analysis used sophisticated imaging to track brain activity across multiple regions involved in appetite control.
The findings support the potential for targeted therapies focusing on amylin pathways for obesity management.
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Gezginer et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76710badf0bb9e87df7f9
https://doi.org/https://doi.org/10.5167/uzh-290762
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