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Recent advances in GABAA receptor targeting ligands | Synapse
March 3, 2026
Recent advances in GABAA receptor targeting ligands
YZ
Yuanyan Zuo
YZ
Yilan Zhao
GL
Genyan Liu
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Puntos clave
GABAA receptor targeting ligands significantly influence neurotransmission, enhancing potential pharmacological effects.
Recent progress had led to the identification of novel ligands, with improved selectivity and efficacy observed in initial tests.
Insights gained from pharmacological data support the development of compounds that can modulate GABAA receptor activity effectively.
Findings imply a strong connection between ligand structure and receptor interactions, opening doors for new therapeutic strategies.
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Zuo et al. (Fri,) studied this question.
synapsesocial.com/papers/69a76717badf0bb9e87df90f
https://doi.org/https://doi.org/10.1016/j.ejmech.2026.118651
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