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Hypoxia-inducible factor signaling regulates embryonic interneuron development, GRIN2B expression and adult cortical function | Synapse
March 3, 2026
Hypoxia-inducible factor signaling regulates embryonic interneuron development, GRIN2B expression and adult cortical function
IL
I-Ling Lu
MS
Mengyi Song
CR
Cinthia Rangel-Sandoval
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Puntos clave
Hypoxia-inducible factor signaling regulates interneuron development, impacting adult cortical function.
A significant finding reveals that GRIN2B expression is influenced by these signaling pathways.
Observational analysis of gene expression and signaling pathways highlights their role in brain development.
These findings support the importance of hypoxia-inducible factor mechanisms in maintaining cortical health.
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Cite This Study
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Lu et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76735badf0bb9e87e0031
https://doi.org/https://doi.org/10.1016/j.devcel.2026.01.007