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Gene-targeted versus broad-spectrum therapies in ALS: comparative lessons and strategic outlook | Synapse
March 3, 2026
Gene-targeted versus broad-spectrum therapies in ALS: comparative lessons and strategic outlook
YS
Y. R. Shen
University of Science and Technology of China
SS
Siyu Shen
ZL
Zhen-Ge Luo
Puntos clave
Gene-targeted therapies may offer more precise intervention opportunities in amyotrophic lateral sclerosis.
Broad-spectrum therapies have shown variable success, with key biomarkers influencing treatment pathways.
Assessment of molecular pathways reveals distinct mechanisms of action between treatment types for ALS.
Insights from this analysis may enable more effective treatment strategies to be developed in ALS management.
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Cite This Study
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Shen et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7674cbadf0bb9e87e05a2
https://doi.org/https://doi.org/10.1016/j.jgg.2026.01.012