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SLL-023ACP, a KOR/MOR dual agonist, produces potent antinociception with fewer side effects | Synapse
March 3, 2026
SLL-023ACP, a KOR/MOR dual agonist, produces potent antinociception with fewer side effects
YS
Yi-quan Shen
PL
Pan-Wen Liu
QG
Qi Guo
Capital Institute of Pediatrics
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Puntos clave
SLL-023ACP produces potent antinociception with a significant reduction in side effects related to opioids.
In tests, SLL-023ACP showed a notable improvement in pain relief compared to traditional opioid agonists.
The study utilized pharmacological assessments to evaluate both efficacy and safety of SLL-023ACP in pain models.
This dual agonist approach may enhance pain management while minimizing the risks typically associated with opioid therapies.
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Shen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a767b8badf0bb9e87e2118
https://doi.org/https://doi.org/10.1016/j.bbrc.2026.153411
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