Geum japonicum Thunb. var. Chinese-P.decorata H.Andres herbal pair ameliorates CIRI-induced neuronal injury by facilitating mitochondrial transfer via the CD38/Miro1 signaling pathway

Puntos clave

• Mitochondrial transfer significantly reduces neuronal injury associated with CIRI, highlighting its protective role.
• The CD38/Miro1 signaling pathway is crucial for the facilitated mitochondrial transfer observed in the study.
• Assessment involved both in vitro and in vivo approaches to ensure consistency and robustness in findings.
• These findings suggest Geum japonicum could offer new avenues for treating neuronal injuries.