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The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder. | Synapse
March 3, 2026
Open Access
The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder.
SH
Sami Ben Hamida
SS
Sarojini M. Sengupta
Southern Illinois University Carbondale
EC
Ellie Clarke
Alder Hey Children's NHS Foundation Trust
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Puntos clave
Impulsivity is significantly influenced by GPR88, indicating its potential role in attention-deficit/hyperactivity disorder (ADHD).
Changes in neurotransmission related to GPR88 were measured, revealing notable behavioral traits linked to impulsivity.
Assessment involved behavioral analysis across ADHD-affected individuals and emphasized GPR88's importance in impulsive behaviors.
Understanding GPR88's function could lead to new insights into ADHD, highlighting a possible therapeutic target in future research.
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Hamida et al. (Fri,) studied this question.
synapsesocial.com/papers/69a767c8badf0bb9e87e2552
https://doi.org/https://doi.org/10.17863/cam.125613
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