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Dendritic spine dysgenesis in spinal cord injury: A structural contributor to pain and spasticity | Synapse
March 3, 2026
Dendritic spine dysgenesis in spinal cord injury: A structural contributor to pain and spasticity
SK
Sierra D. Kauer
PE
Philip R. Effraim
Yale New Haven Hospital
LB
Lakshmi Bangalore
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Puntos clave
Pain and spasticity are linked to structural changes in dendritic spines.
In spinal cord injury, altered spine morphology influences pain pathways.
Observational analysis highlights potential neurobiological mechanisms.
Research suggests targeting dendritic spine integrity may improve outcomes.
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Kauer et al. (Thu,) studied this question.
synapsesocial.com/papers/69a767d2badf0bb9e87e27f8
https://doi.org/https://doi.org/10.1016/j.expneurol.2026.115679