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Deciphering Persistent Prefrontal Cortex Kynurenic Acid Alterations and Molecular Shifts in Adult Mice Following Adolescent THC Exposure | Synapse
March 3, 2026
Deciphering Persistent Prefrontal Cortex Kynurenic Acid Alterations and Molecular Shifts in Adult Mice Following Adolescent THC Exposure
FF
Francesca Frescura
University of Ferrara
ET
Edoardo Tiziani
University of Ferrara
LF
Luca Ferraro
Sapienza University of Rome
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Puntos clave
Kynurenic acid levels in the prefrontal cortex significantly altered after THC exposure during adolescence.
The research indicated that molecular shifts occur in adult mice due to early THC exposure, affecting brain function.
Analysis of biochemical pathways demonstrates ongoing changes in neurotransmitter levels following adolescent THC exposure.
These findings highlight potential long-term impacts of early THC on neurodevelopment and adult behavior.
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Frescura et al. (Thu,) studied this question.
synapsesocial.com/papers/69a7686fbadf0bb9e87e4aa3
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