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CAR-mediated release of IL-10 increases the function of regulatory T cells: relevance for future clinical application | Synapse
March 3, 2026
CAR-mediated release of IL-10 increases the function of regulatory T cells: relevance for future clinical application
AS
Adeel Saleem
COMSATS University Islamabad
PQ
Peng Qi
Xinyang Normal University
ZT
Ziqin Tang
Princess Máxima Center
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Puntos clave
Enhanced regulatory t cell activity is observed with increased IL-10 release.
A notable increase in immune function was reported, correlating with CAR modulation.
Analysis focuses on the role of CAR in cytokine release and its effect on immune cells.
Findings highlight the potential for improved therapies targeting regulatory T cells.
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Cite This Study
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Saleem et al. (Sun,) studied this question.
synapsesocial.com/papers/69a768a3badf0bb9e87e56a2
https://doi.org/https://doi.org/10.1016/j.ymthe.2026.02.001