What does this research mean for the field?

Intranasal oxytocin does not have a meaningful effect on trusting behavior. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

What question did this study set out to answer?

To assess the effect of intranasal oxytocin on trusting behavior using a rigorous equivalence testing framework.

March 5, 2026Open Access

Recommendation of: Absence of a meaningful effect of intranasal oxytocin on trusting behavior: a registered report with pooled equivalence testing. Round#2

Puntos clave

To assess the effect of intranasal oxytocin on trusting behavior using a rigorous equivalence testing framework.
Conducted pooled equivalence testing on multiple studies examining oxytocin's effect.
Analyzed behavioral outcomes related to trust across various scenarios.
Registered report format to ensure transparency in methodology.
Results indicate no meaningful effect of intranasal oxytocin on trusting behavior.
Equivalence testing confirms effects were statistically insignificant.
Implications suggest reconsideration of oxytocin's role in promoting trust.

Resumen

A recommendation of: Charlotte F. Kroll, Koen Schruers, Wolfgang Viechtbauer, Claudia Vingerhoets, Leonie Seidel, Arno Riedl, Dennis Hernaus Absence of a meaningful effect of intranasal oxytocin on trusting behavior: a registered report with pooled equivalence testing https://osf.io/94vrb/files/twd3c

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