INTRODUCTION The immune status of patients with sepsis changes dynamically across different stages, involving complex interactions among multiple immune cells and molecular mechanisms. A dysregulated balance between pro-inflammatory and anti-inflammatory responses can generate sepsis-induced immunosuppression.() A persistent immunosuppressive state is characterized by immune cell exhaustion, particularly in mononuclear cells, whereas late-stage mortality is frequently associated …
Rihl et al. (Thu,) studied this question.