May 25, 1999Open Access

Activation of Cardiac Aldosterone Production in Rat Myocardial Infarction

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Resumen

MI is associated with tissue-specific activation of myocardial aldosterone synthesis. This increase is mediated primarily by cardiac angiotensin II via AT1-subtype receptor and may be involved in post-MI ventricular fibrosis and in control of tissue norepinephrine concentration.

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Silvestre et al. (Tue,) studied this question.

synapsesocial.com/papers/69af0aefe03f6d79082a8c73 https://doi.org/https://doi.org/10.1161/01.cir.99.20.2694

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