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Maternal Metabolic Predictors of Septal Hypertrophy in Infants of Diabetic Mothers | Synapse
March 9, 2026
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Maternal Metabolic Predictors of Septal Hypertrophy in Infants of Diabetic Mothers
EL
Eliezer Lasry
PZ
Patrick Zacharias
AD
Alex M. Dombrower
Keck Hospital of USC
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The research aims to identify metabolic factors in mothers that predict the risk of septal hypertrophy in their infants born to diabetic mothers.
Analyzed maternal metabolic data and infant echocardiograms for septal hypertrophy.
Included a sample of infants born to diabetic mothers to assess the relationship between maternal metabolism and infant cardiac outcomes.
Utilized statistical methods to determine the significance of metabolic predictors.
Higher maternal glucose levels correlate with increased incidence of septal hypertrophy in infants (OR 2.5, 95% CI 1.3-4.8, p=0.005).
Elevated maternal triglycerides were associated with a 1.8-fold increase in risk (95% CI 1.1-3.0, p=0.04).
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Lasry et al. (Thu,) studied this question.
synapsesocial.com/papers/69af23813eac3accde8a1780
https://doi.org/https://doi.org/10.1016/j.metabol.2026.156538