Vitamin D supplementation during pregnancy and offspring bone microarchitecture: A post hoc analysis of the MAVIDOS randomised controlled trial | Synapse
March 12, 2026Open Access
Vitamin D supplementation during pregnancy and offspring bone microarchitecture: A post hoc analysis of the MAVIDOS randomised controlled trial
Puntos clave
The aim is to investigate whether vitamin D supplementation during pregnancy affects offspring bone microarchitecture.
Analyzed data from a subset of children born to mothers in a vitamin D supplementation trial during pregnancy.
Assessed tibial microarchitecture as an outcome measure.
Conducted a post hoc analysis of the MAVIDOS trial participants.
No significant effect of vitamin D supplementation on tibial microarchitecture was observed in the offspring.
Resumen
In this subset of children born to mothers participating in a trial of vitamin D supplementation in pregnancy, no effect of the supplementation on tibial microarchitecture was observed.