Parkinson's Disease increased the risk of cardiovascular-related deaths by 82% compared to those without Parkinson's Disease, with an HR of 1.82 (95% CI 1.24-2.69; p=0.002).
This review highlights a significant but complex interplay between cardiovascular disease and Parkinson's disease, suggesting that cardiovascular comorbidities worsen PD prognosis and mortality.
Estimación del efecto: HR 1.82 (95% CI 1.24-2.69)
valor p: p=0.002
Parkinson's disease (PD) is a common neurodegenerative disorder that is becoming increasingly prevalent in the United States.Current research suggests a possible bidirectional relationship between cardiovascular disease (CVD) and PD.This review aims to synthesize relevant evidence to analyze the interplay between CVD and PD.Researchers utilized academic databases to find current and relevant studies that met the defined inclusion and exclusion criteria.After reviewing various articles, a majority of evidence suggests a correlation between CVD and worsening prognosis for PD patients regarding mortality, cardiac dysfunction, and blood pressure.Conflicting and inconclusive studies are acknowledged within this
George et al. (Mon,) conducted a review in Parkinson's Disease (n=28,242). Parkinson's Disease increased the risk of cardiovascular-related deaths by 82% compared to those without Parkinson's Disease, with an HR of 1.82 (95% CI 1.24-2.69; p=0.002).