HAT-Initiated Fragmentation of 4-(Dimethylamino)-1-((3-methylbut-2-en-1-yl)oxy)-3-phenylbut-3-en-2-one

Puntos clave

• The aim is to synthesize and characterize an alkene-tethered enaminone and investigate its fragmentation.
• Synthesis of the enaminone in four steps from bromoacetic acid and 3,3-dimethylallyl alcohol.
• Full characterization of the enaminone, including UV-Vis spectroscopy.
• TBADT-catalyzed HAT of the enaminone to initiate fragmentation.
• Successfully synthesized and characterized the alkene-tethered enaminone.
• Fragmentation led to the formation of a literature-known phenylacetone-derived enaminone.