Peak stroke volume during maximal exercise negatively correlated with minute ventilation (r=-0.59), carbon dioxide production (r=-0.53), and VO2/FC (r=-0.60) in patients with type 2 diabetes.
What is the relationship between functional capacity and haemodynamic responses to maximal exercise in patients with type II diabetes mellitus?
In patients with type II diabetes, stroke volume performance is negatively correlated with ventilatory parameters during maximal exercise, suggesting a link between cardiovascular performance and reduced exercise capacity.
Tasa de eventos absoluta: 0% vs 0%
Background: Diabetes Mellitus (DM) is a chronic disease that produces negative impact of exercise capacity. Exercise tolerance has been attributed to reduced cardiovascular performance in these patients. Objective: To evaluate the relationship between functional capacity and haemodynamic responses to maximal exercise in DM-II patients. Materials and Methods: 16 patients (49.4±6.2 years) of both sexes we evaluated. Peak stroke volume (SV), cardiac output (CO) and heart rate (HR) by cardioimpedance were measured. Pulmonary gas exchange breath-by-breath was measured during an incremental exercise testing on a cycle. Peak oxygen uptake (VO 2 ), carbon dioxide production (VCO 2 ), minute ventilation (V E ), end tidal carbon dioxide tension (P et CO 2 ) and V E /VCO 2 were compared. Data analysis was used to test for normality Shapiro-Wilk test and Pearson correlation. Results: Significant and negative correlation was observed between SV with V E (r=-0.59), VCO 2 (r=-0.53) and VO 2 /FC (r=-0.60). Conclusion: The results suggest that SV performance is related to exercise capacity in diabetic individuals. These changes would be the harbinger of reduced exercise capacity in diabetics. Financial support: CNPq and FAPESP 2009/01842-0.
Dutra et al. (Sun,) reported a other. Peak stroke volume during maximal exercise negatively correlated with minute ventilation (r=-0.59), carbon dioxide production (r=-0.53), and VO2/FC (r=-0.60) in patients with type 2 diabetes.