Ovarian adenofibroma is a rare benign epithelial tumor that can mimic malignant ovarian neoplasms due to its complex imaging and gross characteristics. We present a 40‐year‐old woman with progressive abdominal pain and a large right adnexal mass, initially suspected as ovarian torsion or malignancy based on sonographic findings of a complex cystic lesion with absent blood flow. Exploratory laparotomy revealed an irregular ovarian mass with papillary vegetations, prompting intraoperative frozen section evaluation. Histopathology confirmed the diagnosis of ovarian cystadenofibroma, composed of fibrous stroma and glandular epithelial elements without cytologic atypia. The patient had an uneventful recovery and remained disease‐free during follow‐up. This case highlights the diagnostic challenges of ovarian adenofibroma, emphasizing the importance of considering this entity in the differential diagnosis of complex adnexal masses and the role of intraoperative frozen section in avoiding unnecessary extensive surgery.
Sattarpour et al. (Thu,) studied this question.