Screening pertactin-specific antibodies and evaluating competitive epitope recognition by native mass spectrometry | Synapse
March 19, 2026Open Access
Screening pertactin-specific antibodies and evaluating competitive epitope recognition by native mass spectrometry
Puntos clave
The research aims to characterize interactions between pertactin-specific antibodies and their antigens to advance vaccine and therapeutic designs.
Screening for pertactin-specific antibodies
Utilizing native mass spectrometry for structural analysis
Evaluating competitive recognition of epitopes
Identified specific antibody recognition patterns
Characterized binding interactions of mAbs
Demonstrated potential for optimizing vaccine efficacy
Resumen
Structural characterization of antigen–antibody interactions is critical for understanding protective vaccine responses and development of therapeutic monoclonal antibodies (mAb).