What question did this study set out to answer?

To highlight the clinical presentation of mechanic's hands in the context of antisynthetase syndrome and its distinct features.

March 21, 2026

Checkerboard Hyperkeratosis With Apoptotic Keratinocytes as Features of Mechanic's Hands and Review of the Literature

Puntos clave

To highlight the clinical presentation of mechanic's hands in the context of antisynthetase syndrome and its distinct features.
Case report of a patient with mechanic's hands
Clinical examination to identify characteristics
Review of existing literature on antisynthetase syndrome and associated skin manifestations.
Identified unique features of checkerboard hyperkeratosis on the patient's hands
Observed apoptotic keratinocytes in the affected skin
Differentiated between mechanic's hands and common dermatological conditions.

Resumen

Antisynthetase syndrome (ASyS), a distinct subset of dermatomyositis, is a heterogeneous entity characterized by multisystem involvement. A classical cutaneous presentation of ASyS is mechanic's hands, manifested by a desquamative papulosquamous eruption afflicting the lateral aspects of fingers. It bears clinical resemblance to common benign simulants such as hand eczema, contact dermatitis, and keratolysis exfoliativa. We outline a case showing features of checkerboard hyperkeratosis with apoptotic keratinocytes and review existing literature.

Preguntar a la IA

Me gusta

Guardar