What question did this study set out to answer?

The aim is to evaluate the effectiveness of heparinized saline compared to contrast media for optical coherence tomography (OCT) during percutaneous coronary interventions.

March 23, 2026Open Access

Saline vs Contrast for Optical Coherence Tomography During Percutaneous Coronary Intervention

Resultado clave

Heparinized saline flushing provides comparable vessel measurements to contrast media for OCT-guided percutaneous coronary intervention without safety concerns.

Puntos clave

The aim is to evaluate the effectiveness of heparinized saline compared to contrast media for optical coherence tomography (OCT) during percutaneous coronary interventions.
Comparison of vessel measurements using heparinized saline and contrast media.
Focus on frequency domain optical coherence tomography (FD-OCT).
Assessment of safety in relation to contrast-induced nephropathy.
Heparinized saline provided similar vessel measurements as contrast media.
Safety concerns with contrast media are alleviated using saline.
Saline is a feasible alternative for OCT-guided PCI, especially for at-risk patients.

PICO estructurado

Does heparinized saline flushing provide comparable vessel measurements to contrast media during OCT-guided PCI?

Población

Patients undergoing OCT-guided PCI

Intervención

Heparinized saline flushing

Comparador

Contrast media

Resultado

Vessel measurementssurrogate

Heparinized saline is a feasible and safe alternative to contrast media for OCT-guided PCI, which may be particularly useful for patients at risk of contrast-induced nephropathy.

Resultado numérico

Tasa de eventos absoluta: 0% vs 0%

Resumen

Heparinized saline provides vessel measurements comparable to contrast media for frequency domain OCT without safety concerns. Saline flushing is a feasible alternative for OCT-guided PCI, particularly in patients at risk of contrast-induced nephropathy.

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Cite This Study

Gupta et al. (Fri,) reported a other. Heparinized saline flushing provides comparable vessel measurements to contrast media for OCT-guided percutaneous coronary intervention without safety concerns.

synapsesocial.com/papers/69c0df0bfddb9876e79c14f6 https://doi.org/https://doi.org/10.1016/j.jacadv.2026.102679

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