Application of chromosomal microarray analysis for fetuses with nasal bone agenesis or hypoplasia

Puntos clave

• The study aims to explore the role of chromosomal microarray analysis in assessing fetal nasal bone agenesis or hypoplasia.
• Evaluate fetal nasal bone structure through imaging
• Perform chromosomal microarray analysis to detect alterations
• Identify associations between nasal defects and chromosomal disorders
• Non-isolated nasal defects correlate with higher rates of chromosomal alterations
• Microdeletions and microinsertions are effectively detected using CMA
• CMA analysis enhances antenatal evaluations for affected fetuses