GPVI deficiency reduces clot size and thrombosis under normoglycemic conditions only, with no effect observed during hyperglycemia.
Does GPVI deficiency reduce clot size and thrombosis in murine models under normoglycaemic versus hyperglycemic conditions?
GPVI mediates thrombosis exclusively under normoglycaemic conditions in mice, indicating that hyperglycemia alters the mechanisms of clot formation.
Tasa de eventos absoluta: 0% vs 0%
Our data suggest that clot formation is affected differentially by absence of GPVI in normo- vs hyperglycemia, supporting a role for GPVI in thrombosis under normoglycaemic conditions only.
Gauer et al. (Mon,) reported a other. GPVI deficiency reduces clot size and thrombosis under normoglycemic conditions only, with no effect observed during hyperglycemia.