Conclusion:In this study of patients hospitalized for CVD and receiving acute-phase CR, an in-hospital decline in CFS was observed in 39.8% of cases.Older age, higher BMI, lower GNRI, ischemic heart disease and HD therapy were independently associated with this decline.These interrelated factors including chronic vulnerability, treatment-related stress, and nutritional imbalance may collectively accelerate frailty progression during hospitalization.Including those on HD, and timely implementation of cardiac rehabilitation may help mitigate further frailty progression and support functional recovery.I have no potential conflict of interest to disclose.I used generative AI and AI-assisted technologies in the writing process.During the preparation of this work, the authors used ChatGPT (OpenAI) solely to improve language and readability.After using this tool,
Kinguchi et al. (Wed,) studied this question.