Long Term Visual Outcomes Following Implantation of a New Hydrophobic IOL in a Real-World Clinical Setting

Purpose: To assess long-term visual and patient-reported outcomes of the CNWTTx (Clareon ® PanOptix ® ) trifocal intraocular lens in a real-world clinical setting. Methods: A retrospective, non-comparative, real-world observational study performed on 70 eyes from 44 patients who underwent standard phacoemulsification and implantation of CNWTT0-T4 trifocal intraocular lens (IOLs) (Alcon Labs, Ft Worth, TX, USA). Postoperative testing was performed at 4– 6 weeks following surgery and included monocular and binocular uncorrected distance (UDVA), intermediate (UIVA) and near (UNVA) visual acuity, distance-corrected intermediate (DCIVA) and near (DCNVA) visual acuity, manifest refraction, best corrected distance visual acuity (BCVA), stereoacuity, spectacle independence and monocular and binocular mesopic contrast sensitivity (CS). Visual symptoms were recorded using a subjective scale (nil, tolerable, bothersome) and satisfaction was recorded using a scale of 1 (least satisfied) to 10 (most satisfied). 6– 12 months postoperative VA data on a subset of patients (N = 35 eyes) was available to monitor continued vision improvement. Results: Manifest refraction spherical equivalent (MRSE) was − 0.12 ± 0.39 D (mean ± SD) with 88% achieving within ± 0.5 D of the refractive target. Postoperative monocular UDVA and BCVA (mean ± SD) were 0.05 ± 0.10 LogMAR and − 0.01 ± 0.07 LogMAR, with 61% and 90% achieving 0.0 LogMAR or better, respectively. Sixty percent of eyes monocularly achieved N5 (approximately 0.18 LogMAR) or better unaided at near, 77% achieved N6 (approximately 0.2 LogMAR) or better at near, and 68.0% achieved N8 (approximately 0.1 to 0.2 LogMAR) or better at intermediate. Mean postoperative binocular CS was 1.67 ± 0.26 and mean stereoacuity was 124.63 ± 124.35 sec arc. Mean subjective satisfaction score was 8.74 ± 1.12. Bothersome glare and halos were reported by 10% and 4.3% of patients, respectively. Full spectacle independence was reported by 92.3% of bilaterally implanted patients. Conclusion: The CNWTTx IOL provides good vision at all ranges with the majority of patients not requiring spectacles for daily tasks. Keywords: multifocal IOL, chord mu, cataract