ABSTRACT Isotretinoin is a highly effective treatment for severe acne, but its use is often complicated by scheduling, pharmacy, and iPLEDGE‐related barriers that may contribute to greater administrative burden for patients facing pre‐existing structural barriers to care. We conducted a cross‐sectional survey study of 42 pediatric patients at an urban safety‐net hospital who had completed at least 1 month of isotretinoin, assessing demographics, treatment experience, and barriers to use. Overall, 64.3% of patients reported appointment, pharmacy, or financial‐related difficulties, contributing to treatment gaps in 33.3%; nevertheless, 97.6% felt their treatment was successful. Despite high perceived efficacy, isotretinoin use was impacted by administrative and iPLEDGE‐related requirements, potentially magnifying existing access barriers.
Lau et al. (Thu,) studied this question.