Objectives: To review current biological, mechanical, and technological strategies aimed at accelerating orthodontic tooth movement. Methods: Published clinical trials, animal studies, and narrative reviews were evaluated to assess surgical, physical, pharmacological, and molecular approaches for enhancing bone remodeling and orthodontic treatment efficiency. Results: Surgical methods such as corticotomy and micro-osteoperforations demonstrated accelerated bone turnover through the regional acceleratory phenomenon. Non-invasive approaches including low-level laser therapy and vibration devices showed promising clinical outcomes. Pharmacological agents and emerging genetic strategies offered targeted modulation of cellular pathways involved in tooth movement. Conclusions: Accelerated orthodontic approaches provide effective strategies to reduce treatment duration while maintaining biological safety. Integration of personalized treatment planning and emerging technologies may further enhance clinical outcomes.
Kushwaha et al. (Sun,) studied this question.