Pulse Explorar nav.journalClub Debates Tendencias Investigadores

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Inicio Explorar nav.journalClub Tendencias

⌘+K

March 29, 2026Open Access

Total chemical synthesis of pentameric cholera toxin subunit B

Puntos clave

The aim is to achieve total chemical synthesis of pentameric cholera toxin subunit B for study purposes.
Chemical synthesis techniques applied to cholera toxin subunit B
Characterization of synthesized biomolecules
Comparison with naturally occurring cholera toxin subunit
Successful synthesis of pentameric cholera toxin subunit B
Characterized subunit shows functional similarities to native form
Findings illuminate potential vaccine development pathways

Resumen

Vibrio cholerae annually infects millions worldwide, causing intense and life-threatening diarrheal disease.

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo

Cite This Study

Spaltenstein et al. (Thu,) studied this question.

synapsesocial.com/papers/69c8c2d1de0f0f753b39d4e0 https://doi.org/https://doi.org/10.1039/d5cc06935a

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins2024 · 47 citations
2The Three-dimensional Crystal Structure of Cholera Toxin1995 · 352 citations
3Total Chemical Synthesis of a D-Enzyme: The Enantiomers of HIV-1 Protease Show Reciprocal Chiral Substrate Specificity1992 · 425 citations
4Serine derived oxazolidines as secondary structure disrupting, solubilizing building blocks in peptide synthesis1992 · 160 citations
5Mirror-Image Gene Transcription and Reverse Transcription2019 · 43 citations

Total chemical synthesis of pentameric cholera toxin subunit B | Synapse