Objective Perinatal mood disorders can seriously endanger the health of pregnant women and fetuses, thus causing heavy burdens and potential hazards to families and society. This study aimed to investigate anxiety and depression in second-trimester pregnant women with cervical insufficiency and provide guidance for clinical practice. Methods A total of 136 second trimester women with cervical insufficiency who underwent laparoscopic cervical cerclage were selected as the observation group, and 117 Pregnant women with no pregnancy complications diagnosed in the second trimester of pregnancy composed the control group. In addition, both online and paper questionnaires were designed to collect basic information. Moreover, Zung’s Self-Rating Anxiety Scale and Self-Rating Depression Scale were employed to evaluate the anxiety and depression of participants in both groups. Results Pregnant women in the cervical insufficiency group had significantly higher Self-rating Anxiety Scale and Self-rating Depression Scale scores than did those in the control group (both P0.001). Compared with those in the control group, a greater percentage of pregnant women in the cervical insufficiency group met the diagnostic criteria for anxiety and depression. The multivariate linear regression model revealed that cervical insufficiency and a history of abnormal pregnancy were related to higher Self-rating Anxiety Scale scores, whereas a history of abnormal pregnancy was also associated with higher Self-rating Depression Scale scores (both P0.05). Conclusion Pregnant women with cervical insufficiency are more likely to suffer from anxiety and depression in the second trimester than normal pregnant women are. Healthcare professionals should pay more attention to these patients in clinical practice.
Chen et al. (2026) studied this question.