Regulation of high‐density cell growth by Rgg transcription factors in Streptococcus thermophilus S‐3

Puntos clave

• The aim is to clarify how rgg genes regulate high-cell-density growth in S. thermophilus S-3.
• Investigated rgg gene function
• Analyzed peptide-mediated quorum sensing initiation
• Examined carbon-nitrogen metabolic flux changes
• Rgg genes play a critical role in high-density cell proliferation
• Quorum sensing mechanisms are coordinated by Rgg
• Metabolic flux is reprogrammed in high-density growth conditions