Interior design is increasingly recognized as a vital contributor to sustainability, particularly in terms of material selection and design behavior that directly impact environmental performance. Although there has been a considerable rise in interest in the subject among academia and professionals, there has not been a cohesive focus on research related to regenerative and biomaterials in interior design. The reasons could be the lack of a clear distinction between biofabrication and conventional regenerative materials, and inadequate exploration of material performance over time. The aim of this study is to explore the research patterns, material strategies, and developments in the themes related to biodesign, regenerative materials, within the context of interior design. The study employed a PRISMA-based systematic literature review of 104 peer-reviewed publications from the year 2000 to 2025. This was followed by a bibliometric analysis employing VOSviewer software in the creation of maps illustrating the publication trends, networks of keywords, and global collaborations in research. The quantitative mapping was done together with the qualitative thematic synthesis. The results show rapid growth in research after 2017, with a strong focus on interior envelope components such as walls and insulation. Biofabricated materials (mycelium, bacterial cellulose, algae) dominate experimental research, while vernacular bio-based materials (bamboo, mud, straw, hemp) remain central to low-impact interior applications. Regenerative interior design is transitioning from sustainable material substitution to biologically and digitally mediated material systems. By distinguishing biofabricated and vernacular regenerative materials and highlighting the role of BIM, digital twins, and performance metrics, this study provides a systems-based framework for scaling regenerative interior materials from experimentation to applied practice.
Tyagi et al. (Mon,) studied this question.