Chronic alcoholics demonstrated a significantly lower coefficient of variation of R-R intervals (3.72) compared to normal controls (5.11), indicating impaired autonomic nervous function.
Case-Control (n=35)
No
Does chronic alcoholism reduce the coefficient of variation of R-R intervals in male patients?
Chronic alcoholism is associated with impaired parasympathetic autonomic function as measured by R-R interval variability, which shows improvement after 4 weeks of abstinence.
Tasa de eventos absoluta: 3.72% vs 5.11%
valor p: p=<0.05
We investigated the coefficient of variation of R-R intervals(CV ratio)in chronic alcoholics to evaluate autonomic nervous function.CV ratio in the patients was significantly lowered compared with that in normal controls.In addition CV ratio of the patients measured within 2 weeks after the cessation of alcohol was lower than that from 4 weeks after the alcohol cessation.However,CV ratio did not correlate with the amount of alcohol drinking.|慢性アルコール症患者の自律神経障害の他覚的指標として,心電図のRーR間隔変動係数(CV値)を調査したところ,CV値は慢性アルコール症患者では正常対象群と比較すると低下しており,さらに断酒後2週間以内に検査したものでは,4週間後に検査したものと比較するとより低値を示した。また,アルコール飲酒量とCV値との間には有意な相関は認められなかった。
元村 et al. (Sun,) conducted a case-control in Chronic alcoholism (n=35). Chronic alcoholism vs. Normal controls was evaluated on Coefficient of variation of R-R intervals (CV ratio) (p=<0.05). Chronic alcoholics demonstrated a significantly lower coefficient of variation of R-R intervals (3.72) compared to normal controls (5.11), indicating impaired autonomic nervous function.