Concurrence of the Core Mechanistic Tenets of the American Heart Association Statement on the Cardiovascular–Kidney–Metabolic Syndrome and the Adipokine Hypothesis of Heart Failure With Preserved Ejection Fraction

Resultado clave

The American Heart Association's mechanistic tenets for cardiovascular-kidney-metabolic syndrome align with the adipokine hypothesis of heart failure with preserved ejection fraction.

Puntos clave

• The aim is to explore the relationship between cardiovascular, kidney, and metabolic syndromes and the adipokine hypothesis in heart failure.
• Literature review of existing statements and hypotheses
• Analysis of the American Heart Association's tenets
• Discussion of the implications of adipokine involvement
• No original data reported
• Identified critical overlaps in mechanistic frameworks
• Highlighted the significance of adipokines in heart failure context