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April 3, 2026Standards1 citationsOpen Access

From Pipettes to p-Values: A Framework for Companion Statistical Reporting in Experimental Neuroscience

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MRMaria Clara Salgado RamosACAlex Oliveira da CamaraHFHércules Rezende Freitas

Key Points

  • The aim is to improve transparency and reproducibility in statistical reporting within experimental neuroscience.
  • Developed the Companion Statistical Report (CSR) as a structured document format.
  • Integrated elements like data provenance, preprocessing decisions, and effect sizes into a single document.
  • Utilized Quarto 1.8 for creating CSRs that work with R and Python workflows.
  • Provided an open template on GitHub for public use and customization.
  • CSRs allow for auditable analytic choices in neuroscience experiments.
  • The framework helps bridge the gap between experimental measurements and reported statistics.
  • Designed to enhance reproducibility and support peer review processes.

Abstract

Statistical inference in experimental neuroscience is routinely detached from the experimental record: analytic choices are reported in prose summaries that do not expose the code, assumptions, or decision pathways that produced the results. This detachment limits reproducibility and impairs peer review. Here, we describe the Companion Statistical Report (CSR), a structured, versioned document format designed to accompany empirical neuroscience manuscripts as peer-reviewed as a peer-reviewed resource. The CSR integrates data provenance, preprocessing decisions, exploratory analyses, model specifications, assumption diagnostics, inference with effect sizes, and sensitivity analyses into a single executable document, authored in Quarto 1.8 and supporting both R and Python workflows. We provide an open template hosted at on GitHub that implements this format with institutional branding, parameterization, and version tracking. The template was developed by the Bertrand Russell Research Excellence Group (NEC) at the School of Medicine, Rio de Janeiro State University. By making analytic choices auditable and reproducible by design, CSRs are designed to reduce the gap between what neuroscience experiments measure and what published statistics claim, offering a tractable and immediately implementable step toward greater transparency.

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Cite This Study

Ramos et al. (2026) studied this question.

synapsesocial.com/papers/69cf5f425a333a821460e4d5https://doi.org/10.3390/standards6020013
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