What question did this study set out to answer?

The research aims to explore the variability in albuminuria reduction among individuals taking dapagliflozin.

April 4, 2026Open Access

Reduction in Albuminuria with Dapagliflozin Exhibits Substantial Interindividual Variability: A Real-World Study Utilizing a Big Data Approach

Puntos clave

The research aims to explore the variability in albuminuria reduction among individuals taking dapagliflozin.
Conducted a real-world study utilizing big data analysis
Analyzed factors such as duration of T2DM, baseline HbA1c, SBP, and UACR
Performed ROC analysis to assess discriminative ability of identified factors
Notable interindividual variability in albuminuria-lowering effect of dapagliflozin
Duration of T2DM, baseline HbA1c, SBP, and UACR associated with the response
ROC analysis indicated limited discriminative ability for clinical use

Resumen

Significant interindividual variability was observed in the albuminuria-lowering effect of dapagliflozin in the Chinese population. After adjustment for potential confounders, the duration of T2DM, baseline HbA1c, baseline SBP, and baseline UACR were identified as factors associated with the albuminuria response to dapagliflozin. However, their discriminative ability was limited and inadequate for clinical use according to the ROC analysis.

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Cite This Study

Song et al. (Thu,) studied this question.

synapsesocial.com/papers/69d0adc2659487ece0fa4531 https://doi.org/https://doi.org/10.4274/balkanmedj.galenos.2026.2025-12-261

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