Abstract: We have developed an eco-friendly and easy-to-use procedure for the conversion of primary allylic and benzylic alcohols to aldehydes using sodium bismuthate and microwave irradiation. The reaction is carried out with high efficiency, and little to no use of harsh and toxic chemicals of the oxidant can be achieved by performing the reaction in an aqueous solution of acetic acid. Allylic alcohols with varied structures gave good results; primary allylic alcohols gave the desired aldehyde products in good yields. Moreover, the procedure is safe and cost-effective, as it involves simple apparatus and the use of sodium bismuthate as a reactant, along with microwave irradiation, which provides efficient and fast reactions. Therefore, this method provides an eco-friendly, efficient, and economical way of synthesizing aldehydes as per the guidelines of green chemistry.
Shaikh et al. (Tue,) studied this question.