Modeling of Fiber Orientation‐Dependent R1 Relaxation in Human White Matter In Vivo Within The Framework of The Transient Hydrogen Bond Model | Synapse
April 5, 2026Open Access
Modeling of Fiber Orientation‐Dependent R1 Relaxation in Human White Matter In Vivo Within The Framework of The Transient Hydrogen Bond Model
Puntos clave
To explore the relationship between fiber orientation and R1 relaxation in human white matter using the Transient Hydrogen Bond model.
Utilized the Transient Hydrogen Bond model for analysis.
Conducted in vivo measurements of R1 relaxation.
Evaluated the dependence of R1 relaxation on fiber orientation and B0 field.
The model successfully explains R1 relaxation anisotropy in white matter.
Demonstrated dependence of R1 relaxation on B0 field variations.
Resumen
The data show that the THB model provides a robust physical framework for R1 relaxation anisotropy and B0 field dependence in vivo.