Does a single negative troponin test result safely rule out 30-day cardiac mortality and acute myocardial infarction compared to serial troponin testing in patients in the Emergency Department with suspected acute myocardial infarction?
Discharging ED patients with suspected acute myocardial infarction after a single negative troponin test appears safe, with 30-day cardiac mortality and AMI rates comparable to those undergoing serial testing.
This study suggests that patients are routinely discharged from the ED after a single negative troponin test result, and when compared with serial troponin testing, a single troponin test appears safe based on current physician decision-making, with no difference in rates of 30-day cardiac mortality and acute myocardial infarction, which are low in both groups.
Wassie et al. (Tue,) studied this question.