February 6, 2009

Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

Sulfate homeostasis is essential for maintaining a normal intestinal metabolic state, and hyposulfataemia leads to reduced intestinal sulfomucin content, enhanced susceptibility to toxin-induced colitis and impaired intestinal barrier to bacterial infection.

Preguntar a la IA

Me gusta

Guardar

Cite This Study

Dawson et al. (Fri,) studied this question.

synapsesocial.com/papers/69d6f05a5413bc3de5ab3088 https://doi.org/https://doi.org/10.1136/gut.2007.147595

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Muc1 Mucin Limits Both Helicobacter pylori Colonization of the Murine Gastric Mucosa and Associated Gastritis2007 · 197 citations
2MUC17, a Novel Membrane-Tethered Mucin2002 · 218 citations
3Production of mucinase and neuraminidase and binding of Shigella to intestinal mucin.1993 · 24 citations
4Interleukin 10-deficient colitis: new similarities to human inflammatory bowel disease2000 · 137 citations
5Faecal Excretion of Bicarbonate in Ulcerative Colitis2009 · 45 citations

Preguntar a la IA

Me gusta

Guardar