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February 16, 2011Open Access

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

GCGabriella CastoriaUniversity of Campania "Luigi Vanvitelli"LDLoredana D’AmatoUniversity of Naples Federico II ACAlessandra CiociolaHospital del Mar Research Institute

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Resumen

The present report, for the first time, indicates that the extra nuclear AR/FlnA/integrin beta 1 complex is the key by which androgen activates signaling leading to cell migration. Assembly of this ternary complex may control organ development and prostate cancer metastasis.

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Cite This Study

Castoria et al. (Wed,) studied this question.

synapsesocial.com/papers/69d6fc7ef174babf6cab3d54 https://doi.org/https://doi.org/10.1371/journal.pone.0017218

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association | Synapse