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Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury | Synapse

March 30, 2012

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Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

TDTamás DolinayUniversity of California, Los Angeles YKYoung Sam KimChungbuk National University JHJudie A. HowrylakHershey (United States)

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Resumen

The inflammasome pathway and its downstream cytokines play critical roles in ARDS development.

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Cite This Study

Dolinay et al. (Fri,) studied this question.

synapsesocial.com/papers/69d728a58a0e2c5879befb24 https://doi.org/https://doi.org/10.1164/rccm.201201-0003oc

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Discovery of the gene signature for acute lung injury in patients with sepsis2009 · 77 citations
2Role of Proinflammatory Cytokines IL-18 and IL-1β in Bleomycin-Induced Lung Injury in Humans and Mice2009 · 162 citations
3Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf2004 · 1,835 citations
4Experimental and Clinical Studies on Lactate and Pyruvate as Indicators of the Severity of Acute Circulatory Failure (Shock)1970 · 718 citations
5Elevated lnterleukin-1 Release by Human Alveolar Macrophages during the Adult Respiratory Distress Syndrome1989 · 160 citations