January 29, 2016Open Access

Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes

NGNorbert GerdesDüsseldorf University Hospital TSTom SeijkensThe Netherlands Cancer Institute DLDirk LievensAmsterdam UMC Location University of Amsterdam

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Resumen

Platelet CD40 plays a crucial role in inflammation by stimulating leukocyte activation and recruitment and activation of endothelial cells, thereby promoting atherosclerosis.

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Gerdes et al. (Fri,) studied this question.

synapsesocial.com/papers/69d72e935dca7d66cbbef2cb https://doi.org/https://doi.org/10.1161/atvbaha.115.307074

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