Thio-Click Modification of Poly2-(3-butenyl)-2-oxazoline

The radical addition of mercaptans (RSH) onto poly2-(3-butenyl)-2-oxazoline, which is available through a living/controlled cationic isomerization polymerization, can proceed smoothly in the absence of side reactions, exhibiting the characteristics of a click reaction. The “thio-click” reaction can be performed under feasible (RSH/CC ∼ 1.2−1.5, no transition metal additives) and mild conditions (generation of radicals with UV light at room temperature) and goes to completion within a day. Hydrophobic fluoropolymers can be prepared in the same way as water-soluble (co-)polymers or glycopolymers, starting from readily available materials.