April 24, 2019Open Access

Amelioration of muscle wasting by glucagon‐like peptide‐1 receptor agonist in muscle atrophy

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

GLP-1R agonists ameliorate muscle wasting by suppressing MSTN and muscle atrophic factors and enhancing myogenic factors through GLP-1R-mediated signalling pathways. These novel findings suggest that activating GLP-1R signalling may be useful for the treatment of atrophy-related muscular diseases.

Leer artículo completoexternamente

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo

Cite This Study

Hong et al. (Wed,) studied this question.

synapsesocial.com/papers/69d752d8f182769aa8b8a4f4 https://doi.org/https://doi.org/10.1002/jcsm.12434

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease2011 · 307 citations
2Disease-Induced Skeletal Muscle Atrophy and Fatigue2016 · 209 citations
3THE NF-κB AND IκB PROTEINS: New Discoveries and Insights1996 · 5,966 citations
4Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways2001 · 1,571 citations
5Glucocorticoid Signaling in the Arcuate Nucleus Modulates Hepatic Insulin Sensitivity2011 · 68 citations

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo