Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Puntos clave

• To assess the global, regional, and national burden of stroke and its attributable risk factors from 1990 to 2021.
• Systematic epidemiological assessment using data from the Global Burden of Disease Study 2021 across 204 countries and territories.
• Estimated stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and attributable risk factor burdens over a 31-year period.
• Stroke remains a primary contributor to mortality and long-term disability worldwide, with substantial disparities across geographic regions and socio-demographic tiers.
• A substantial portion of the global stroke burden continues to be driven by modifiable behavioral, environmental, and metabolic risk factors.