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ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers | Synapse

January 4, 2012Open Access

ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

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Resumen

ROS1 rearrangement defines a molecular subset of NSCLC with distinct clinical characteristics that are similar to those observed in patients with ALK-rearranged NSCLC. Crizotinib shows in vitro activity and early evidence of clinical activity in ROS1-rearranged NSCLC.

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Cite This Study

Bergethon et al. (Wed,) studied this question.

synapsesocial.com/papers/69d76859aa68b335b4f31555 https://doi.org/https://doi.org/10.1200/jco.2011.35.6345