To clarify the construct of certainty of evidence and recommend explicit specification of thresholds or ranges when assessing scientific confidence.
GRADE Working Group established updated methodological guidance for systematic review authors, clinical guideline panels, and health technology assessors.
Evidence assessors are advised to explicitly define and report the specific numerical or conceptual thresholds and ranges used when rating certainty in evidence.
Abstract
It is desirable for systematic review authors, guideline panelists, and health technology assessors to specify the threshold or ranges they are using when rating the certainty in evidence.