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In men with BCR and low PSA, 89ZrZr-PSMA-617 PET/CT seems effective in finding prostate malignancy not seen on 68GaGa-PSMA-11 PET/CT. The higher detection rates and lesion-to-background ratios of 48-h scans versus 24-h scans suggest that imaging at the later time may be preferable. Prospective study of 89ZrZr-PSMA-617 PET/CT is warranted.
Rosar et al. (Sat,) studied this question.
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