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October 20, 2005Open Access

Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer

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Resumen

Trastuzumab combined with paclitaxel after doxorubicin and cyclophosphamide improves outcomes among women with surgically removed HER2-positive breast cancer. (ClinicalTrials.gov numbers, NCT00004067 and NCT00005970.)

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Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer | Synapse

Cite This Study

Romond et al. (Thu,) studied this question.

synapsesocial.com/papers/69d7b52fb843b2be9949075a https://doi.org/https://doi.org/10.1056/nejmoa052122

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Assessment of Cardiac Dysfunction in a Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed by Paclitaxel, With or Without Trastuzumab As Adjuvant Therapy in Node-Positive, Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer: NSABP B-312005 · 807 citations
2Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial2002 · 1,961 citations
3Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene1987 · 11,749 citations
4Cardiac Dysfunction in the Trastuzumab Clinical Trials Experience2002 · 532 citations
5HER2 and Choice of Adjuvant Chemotherapy for Invasive Breast Cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-152000 · 306 citations